Structure of PDB 3d5f Chain A

Receptor sequence
>3d5fA (length=254) Species: 9606 (Homo sapiens) [Search protein sequence]
LKAFSKHIYNAYLKNFNMTKKKARSILTGPFVIHDIETLWQAEKGLVWLP
PYKEISVHVFYRCQCTTVETVRELTEFAKSIPSFSSLFLNDQVTLLKYGV
HEAIFAMLASIVNKDGLLVANGSGFVTREFLRSLRKPFSDIIEPKFEFAV
KFNALELDDSDLALFIAAIILCGDRPGLMNVPRVEAIQDTILRALEFHLQ
ANHPDAQQLFPKLLQKMADLRQLVTEHAQMMQRIKKTETETSLHPLLQEI
YKDM
3D structure
PDB3d5f PPAR-Delta Activation Contributes to Neuroprotectio Against Thapsigargin-Induced SH-SY5Y Cell Death
ChainA
Resolution2.2 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 L41 A R284 C285 T288 T289 H323 L330 L339 V341 H449 L469 R62 C63 T66 T67 H101 L108 L117 V119 H227 L247 BindingDB: EC50=39nM,IC50=13nM,Kd=0.430000nM
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0004879 nuclear receptor activity
Biological Process
GO:0006355 regulation of DNA-templated transcription
Cellular Component
GO:0005634 nucleus

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:3d5f, PDBe:3d5f, PDBj:3d5f
PDBsum3d5f
PubMed
UniProtQ03181|PPARD_HUMAN Peroxisome proliferator-activated receptor delta (Gene Name=PPARD)

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