Structure of PDB 3d06 Chain A

Receptor sequence
>3d06A (length=179) Species: 9606 (Homo sapiens) [Search protein sequence]
VPSQKTYQGSYGFRLGFLVTCTYSPALNKMFCQLAKTCPVQLWVDSTPPP
GTRVRAMAIYKQSQHMTEVVRRCPHHERLAPPQHLIRVEGNLRVEYLDDR
NTFRHSVVVPYEPPEVGSDCTTIHYNYMCNSSCMGGMNRSPILTIITLED
SSGNLLGRNSFEVRVCACPGRDRRTEEEN
3D structure
PDB3d06 Structural basis of restoring sequence-specific DNA binding and transactivation to mutant p53 by suppressor mutations
ChainA
Resolution1.2 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 ZN A C176 H179 C242 C73 H76 C133
Gene Ontology
Molecular Function
GO:0000976 transcription cis-regulatory region binding
GO:0003677 DNA binding
GO:0003700 DNA-binding transcription factor activity
Biological Process
GO:0006355 regulation of DNA-templated transcription
GO:0006915 apoptotic process
Cellular Component
GO:0005634 nucleus

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Molecular Function

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Biological Process

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Cellular Component
External links
PDB RCSB:3d06, PDBe:3d06, PDBj:3d06
PDBsum3d06
PubMed18996393
UniProtP04637|P53_HUMAN Cellular tumor antigen p53 (Gene Name=TP53)

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