Structure of PDB 3czf Chain A

Receptor sequence

>3czfA (length=275) Species: 9606 (Homo sapiens) [Search protein sequence]

GSHSMRYFHTSVSRPGRGEPRFITVGYVDDTLFVRFDSDAASPREEPRAP
WIEQEGPEYWDRETQICKAKAQTDREDLRTLLRYYNQSEAGSHTLQNMYG
CDVGPDGRLLRGYHQHAYDGKDYIALNEDLSSWTAADTAAQITQRKWEAA
RVAEQLRAYLEGECVEWLRRYLENGKETLQRADPPKTHVTHHPISDHEAT
LRCWALGFYPAEILTWQRDGEDQTQDTELVETRPAGDRTFQKWAAVVVPS
GEEQRYTCHVQHEGLPKPLTLRWEP

3D structure

PDB

3czf Conformational Plasticity of HLA-B27 Molecules Correlates Inversely With Efficiency of Negative T Cell Selection.

Chain

Resolution

1.2 Å

3D
structure

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Enzymatic activity

Enzyme Commision number

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	peptide	A	Y7 H9 T24 E45 R62 E63 Q65 I66 C67 T73 E76 D77 Y84 Y99 H114 T143 K146 W147 V152 Q155 L156 Y159 E163 W167 Y171	Y7 H9 T24 E45 R62 E63 Q65 I66 C67 T73 E76 D77 Y84 Y99 H114 T143 K146 W147 V152 Q155 L156 Y159 E163 W167 Y171

External links

PDB	RCSB:3czf, PDBe:3czf, PDBj:3czf
PDBsum	3czf
PubMed	32117305
UniProt	P01889\|HLAB_HUMAN HLA class I histocompatibility antigen, B alpha chain (Gene Name=HLA-B)

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