Structure of PDB 3cyy Chain A

Receptor sequence
>3cyyA (length=80) Species: 9606 (Homo sapiens) [Search protein sequence]
KPTKVTLVKSAKNEEYGLRLASHIFVKEISQDSLAARDGNIQEGDVVLKI
NGTVTENMSLTDAKTLIERSKGKLKMVVQR
3D structure
PDB3cyy Domain-swapped dimerization of ZO-1 PDZ2 generates specific and regulatory connexin43-binding sites
ChainA
Resolution2.4 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 peptide A K209 K246 K27 K64
BS02 peptide A E197 Y198 L200 R201 L202 E238 N239 E15 Y16 L18 R19 L20 E56 N57
External links
PDB RCSB:3cyy, PDBe:3cyy, PDBj:3cyy
PDBsum3cyy
PubMed18636092
UniProtQ07157|ZO1_HUMAN Tight junction protein ZO-1 (Gene Name=TJP1)

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