Structure of PDB 3csw Chain A

Receptor sequence
>3cswA (length=274) Species: 243274 (Thermotoga maritima MSB8) [Search protein sequence]
HVLIWWRGKFRRADEISLDFSLFEKSLQGAVYETLRTYSRAPFAAYKHYT
RLKRSADFFNLPLSLSFDEFTKVLKAGADEFKQEVRIKVYLFPDSGEVLF
VFSPLNIPDLETGVEVKISNVRRIPDLSTPPALKITGRTDIVLARREIVD
CYDVILLGLNGQVCEGSFSNVFLVKEGKLITPSLDSGILDGITRENVIKL
AKSLEIPVEERVVWVWELFEADEMFLTHTSAGVVPVRRLNEHSFFEEEPG
PVTATLMENFEPFVLNLEENWVGI
3D structure
PDB3csw Crystal structure of a Putative Branched-Chain Amino Acid Aminotransferase (TM0831) from Thermotoga maritima at 2.15 A resolution
ChainA
Resolution2.15 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) Y31 K133 E164 L188
Catalytic site (residue number reindexed from 1) Y32 K134 E165 L189
Enzyme Commision number 2.6.1.42: branched-chain-amino-acid transaminase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 PLP A R50 K133 E164 F167 S168 L188 G190 I191 T192 T228 R51 K134 E165 F168 S169 L189 G191 I192 T193 T229
Gene Ontology
Molecular Function
GO:0003824 catalytic activity
GO:0008483 transaminase activity
GO:0052654 L-leucine-2-oxoglutarate transaminase activity
GO:0052655 L-valine-2-oxoglutarate transaminase activity
GO:0052656 L-isoleucine-2-oxoglutarate transaminase activity
Biological Process
GO:0008652 amino acid biosynthetic process
GO:0009082 branched-chain amino acid biosynthetic process
GO:0009097 isoleucine biosynthetic process
GO:0009098 L-leucine biosynthetic process
GO:0009099 L-valine biosynthetic process
GO:0019752 carboxylic acid metabolic process
GO:0046394 carboxylic acid biosynthetic process

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Molecular Function
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Biological Process
External links
PDB RCSB:3csw, PDBe:3csw, PDBj:3csw
PDBsum3csw
PubMed
UniProtP74921|ILVE_THEMA Probable branched-chain-amino-acid aminotransferase (Gene Name=ilvE)

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