Structure of PDB 3crx Chain A

Receptor sequence

>3crxA (length=323) Species: 10678 (Punavirus P1) [Search protein sequence]

TSDEVRKNLMDMFRDRQAFSEHTWKMLLSVCRSWAAWCKLNNRKWFPAEP
EDVRDYLLYLQARGLAVKTIQQHLGQLNMLHRRSGLPRPSDSNAVSLVMR
RIRKENVDAGERAKQALAFERTDFDQVRSLMENSDRCQDIRNLAFLGIAY
NTLLKIAEIARIRVKDISRTDGGRMLIHIGRTKTLVSTAGVEKALSLGVT
KLVERWISVSGVADDPNNYLFCRVRKNGVAAPSATSQLSTRALEGIFEAT
HRLIYGAKDDSGQRYLAWSGHSARVGAARDMARAGVSIPEIMQAGGWTNV
NIVMNYIRNLDSETGAMVRLLED

3D structure

PDB

3crx Structure of the Holliday junction intermediate in Cre-loxP site-specific recombination.

Chain

Resolution

2.5 Å

3D
structure

[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]

Enzymatic activity

Enzyme Commision number

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	dna	A	M44 S47 R81 L83 A84 K86 T87 A131 K132 Q156 R159 T202 R241 V242 R243 K244 L256 S257 R259 R282 I320 Y324	M26 S29 R63 L65 A66 K68 T69 A113 K114 Q138 R141 T184 R223 V224 R225 K226 L238 S239 R241 R264 I302 Y306
BS02	dna	A	F37 S38 H40 T41 M97 I174 A175 R243 K244 R259 E262 Y283 S287 G288 H289	F19 S20 H22 T23 M79 I156 A157 R225 K226 R241 E244 Y265 S269 G270 H271

Gene Ontology

	Molecular Function
GO:0003677	DNA binding

	Biological Process
GO:0006310	DNA recombination
GO:0015074	DNA integration

View graph for
Molecular Function

View graph for
Biological Process

External links

PDB	RCSB:3crx, PDBe:3crx, PDBj:3crx
PDBsum	3crx
PubMed	9670032
UniProt	P06956\|RECR_BPP1 Recombinase cre (Gene Name=cre)

[Back to BioLiP]