Structure of PDB 3cpo Chain A

Receptor sequence
>3cpoA (length=122) Species: 303 (Pseudomonas putida) [Search protein sequence]
LPTAQEVQGLMARYIELVDVGDIEAIVQMYADDATVENPFGQPPIHGREQ
IAAFYRQGLKVRACLTGPVRASHNGCGAMPFRVEMVWNGQPCALDVIDVM
RFDEHGRIQTMQAYWSEVNLSV
3D structure
PDB3cpo Testing geometrical discrimination within an enzyme active site: constrained hydrogen bonding in the ketosteroid isomerase oxyanion hole
ChainA
Resolution1.24 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) Y16 N40 D100 D103
Catalytic site (residue number reindexed from 1) Y14 N38 D95 D98
Enzyme Commision number 5.3.3.1: steroid Delta-isomerase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 FP2 A Y16 V20 N40 F86 V101 D103 Y14 V18 N38 F81 V96 D98
Gene Ontology
Molecular Function
GO:0004769 steroid delta-isomerase activity
GO:0016853 isomerase activity
Biological Process
GO:0008202 steroid metabolic process

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Molecular Function
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Biological Process
External links
PDB RCSB:3cpo, PDBe:3cpo, PDBj:3cpo
PDBsum3cpo
PubMed18808119
UniProtP07445|SDIS_PSEPU Steroid Delta-isomerase (Gene Name=ksi)

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