Structure of PDB 3cmu Chain A

Receptor sequence
>3cmuA (length=1937) Species: 83333 (Escherichia coli K-12) [Search protein sequence]
VETISTGSLSLDIALGAGGLPMGRIVEIYGPESSGKTTLTLQVIAAAQRE
GKTCAFIDAEHALDPIYARKLGVDIDNLLCSQPDTGEQALEICDALARSG
AVDVIVVDSVAALTPKAEIEGEIGDSHMGLAARMMSQAMRKLAGNLKQSN
TLLIFINQIRMKIGVMFGNPETTTGGNALKFYASVRLDIRRIGAVKEGEN
VVGSETRVKVVKNKIAAPFKQAEFQILYGEGINFYGELVDLGVKEKLIEK
AGAWYSYKGEKIGQGKANATAWLKDNPETAKEIEKKVRELLLAIDENKQK
ALAAALGQIEKQFGKGSIMRLGEDRSMDVETISTGSLSLDIALGAGGLPM
GRIVEIYGPESSGKTTLTLQVIAAAQREGKTCAFIDAEHALDPIYARKLG
VDIDNLLCSQPDTGEQALEICDALARSGAVDVIVVDSVAALTPKAEIEGE
IGDSHMGLAARMMSQAMRKLAGNLKQSNTLLIFINQIRMKIGVMFGNPET
TTGGNALKFYASVRLDIRRIGAVKEGENVVGSETRVKVVKNKIAAPFKQA
EFQILYGEGINFYGELVDLGVKEKLIEKAGAWYSYKGEKIGQGKANATAW
LKDNPETAKEIEKKVRELLLSNPNSAIDENKQKALAAALGQIEKQFGKGS
IMRLGEDRSMDVETISTGSLSLDIALGAGGLPMGRIVEIYGPESSGKTTL
TLQVIAAAQREGKTCAFIDAEHALDPIYARKLGVDIDNLLCSQPDTGEQA
LEICDALARSGAVDVIVVDSVAALTPKAEIEGEIGDSHMGLAARMMSQAM
RKLAGNLKQSNTLLIFINQIRMKIGVMFGNPETTTGGNALKFYASVRLDI
RRIGAVKEGENVVGSETRVKVVKNKIAAPFKQAEFQILYGEGINFYGELV
DLGVKEKLIEKAGAWYSYKGEKIGQGKANATAWLKDNPETAKEIEKKVRE
LLLSNPNSAIDENKQKALAAALGQIEKQFGKGSIMRLGEDRSMDVETIST
GSLSLDIALGAGGLPMGRIVEIYGPESSGKTTLTLQVIAAAQREGKTCAF
IDAEHALDPIYARKLGVDIDNLLCSQPDTGEQALEICDALARSGAVDVIV
VDSVAALTPKAEIEGEIGDSHMGLAARMMSQAMRKLAGNLKQSNTLLIFI
NQIRMKIGVMFGNPETTTGGNALKFYASVRLDIRRIGAVKEGENVVGSET
RVKVVKNKIAAPFKQAEFQILYGEGINFYGELVDLGVKEKLIEKAGAWYS
YKGEKIGQGKANATAWLKDNPETAKEIEKKVRELLLSNPNSAIDENKQKA
LAAALGQIEKQFGKGSIMRLGEDRSMDVETISTGSLSLDIALGAGGLPMG
RIVEIYGPESSGKTTLTLQVIAAAQREGKTCAFIDAEHALDPIYARKLGV
DIDNLLCSQPDTGEQALEICDALARSGAVDVIVVDSVAALTPKAEIEGEI
GDSHMGLAARMMSQAMRKLAGNLKQSNTLLIFINQIRMKIGVMFGNPETT
TGGNALKFYASVRLDIRRIGAVKEGENVVGSETRVKVVKNKIAAPFKQAE
FQILYGEGINFYGELVDLGVKEKLIEKAGAWYSYKGEKIGQGKANATAWL
KDNPETAKEIEKKVRELLLSNPNSAIDENKQKALAAALGQIEKQFGKGSI
MRLGEDRSMDVETISTGSLSLDIALGAGGLPMGRIVEIYGPESSGKTTLT
LQVIAAAQREGKTCAFIDAEHALDPIYARKLGVDIDNLLCSQPDTGEQAL
EICDALARSGAVDVIVVDSVAALTPKAEIEMGLAARMMSQAMRKLAGNLK
QSNTLLIFINQIRNPETTTGGNALKFYASVRLDIRRIGAVKEGENVVGSE
TRVKVVKNKIAAPFKQAEFQILYGEGINFYGELVDLGVKEKLIEKAGAWY
SYKGEKIGQGKANATAWLKDNPETAKEIEKKVRELLL
3D structure
PDB3cmu Mechanism of homologous recombination from the RecA-ssDNA/dsDNA structures.
ChainA
Resolution4.2 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 dna A R196 M197 K198 I199 G200 G1165 A1168 S1172 R1176 R1196 M1197 K1198 I1199 G1211 G1212 N1213 G2165 A2168 R2169 S2172 R2176 R2196 M2197 K2198 I2199 G2211 G2212 G3165 A3168 R3169 S3172 R3176 R3196 M3197 K3198 I3199 G3211 G3212 N3213 M4164 G4165 A4168 R4169 S4172 R4176 R4196 M4197 K4198 I4199 G4212 R5169 S5172 R5176 G5212 N5213 R160 M161 K162 I163 G164 G457 A460 S464 R468 R488 M489 K490 I491 G503 G504 N505 G790 A793 R794 S797 R801 R821 M822 K823 I824 G836 G837 G1123 A1126 R1127 S1130 R1134 R1154 M1155 K1156 I1157 G1169 G1170 N1171 M1455 G1456 A1459 R1460 S1463 R1467 R1487 M1488 K1489 I1490 G1503 R1786 S1789 R1793 G1821 N1822
BS02 ALF A E68 K72 E96 F1217 K1248 K1250 E32 K36 E60 F509 K540 K542
BS03 ALF A E1068 K1072 E1096 F2217 K2248 K2250 E360 K364 E388 F842 K873 K875
BS04 MG A T2073 K3250 T698 K1208
BS05 ALF A E2068 K2072 E2096 F3217 K3248 K3250 E693 K697 E721 F1175 K1206 K1208
BS06 ALF A E3068 K3072 E3096 F4217 K4248 K4250 E1026 K1030 E1054 F1508 K1539 K1541
BS07 ALF A E4068 K4072 E4096 F5217 K5248 K5250 E1359 K1363 E1387 F1826 K1857 K1859
BS08 MG A T5073 E5096 T1697 E1720
BS09 ALF A E5068 S5069 K5072 E5096 E1692 S1693 K1696 E1720
BS10 ADP A S69 S70 G71 K72 T73 T74 Y103 Y264 N1249 K1250 I1251 A1252 A1253 P1254 S33 S34 G35 K36 T37 T38 Y67 Y228 N541 K542 I543 A544 A545 P546
BS11 ADP A S1069 S1070 G1071 K1072 T1073 T1074 D1100 Y1103 Y1264 N2249 K2250 I2251 A2252 A2253 P2254 S361 S362 G363 K364 T365 T366 D392 Y395 Y556 N874 K875 I876 A877 A878 P879
BS12 ADP A E2068 S2069 S2070 G2071 K2072 T2073 T2074 Y2103 Y2264 N3249 K3250 I3251 A3252 A3253 P3254 E693 S694 S695 G696 K697 T698 T699 Y728 Y889 N1207 K1208 I1209 A1210 A1211 P1212
BS13 ADP A S3069 S3070 G3071 K3072 T3073 T3074 Y3103 Y3264 N4249 K4250 I4251 A4252 A4253 P4254 S1027 S1028 G1029 K1030 T1031 T1032 Y1061 Y1222 N1540 K1541 I1542 A1543 A1544 P1545
BS14 ADP A S4069 S4070 G4071 K4072 T4073 T4074 Y4103 Y4264 N5249 K5250 I5251 A5252 P5254 S1360 S1361 G1362 K1363 T1364 T1365 Y1394 Y1555 N1858 K1859 I1860 A1861 P1863
BS15 ADP A E5068 S5069 S5070 G5071 K5072 T5073 T5074 D5100 Y5264 E1692 S1693 S1694 G1695 K1696 T1697 T1698 D1724 Y1873
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0003684 damaged DNA binding
GO:0003697 single-stranded DNA binding
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0008094 ATP-dependent activity, acting on DNA
GO:0016887 ATP hydrolysis activity
GO:0140297 DNA-binding transcription factor binding
GO:0140664 ATP-dependent DNA damage sensor activity
Biological Process
GO:0000725 recombinational repair
GO:0006259 DNA metabolic process
GO:0006281 DNA repair
GO:0006310 DNA recombination
GO:0006974 DNA damage response
GO:0009432 SOS response
GO:0010212 response to ionizing radiation
GO:0019985 translesion synthesis
GO:0035825 homologous recombination
GO:0048870 cell motility
Cellular Component
GO:0005737 cytoplasm
GO:0009355 DNA polymerase V complex

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:3cmu, PDBe:3cmu, PDBj:3cmu
PDBsum3cmu
PubMed18497818
UniProtP0A7G6|RECA_ECOLI Protein RecA (Gene Name=recA)

[Back to BioLiP]