Structure of PDB 3ciy Chain A

Receptor sequence
>3ciyA (length=661) Species: 10090 (Mus musculus) [Search protein sequence]
CTVRYNVADCSHLKLTHIPDDLPSNITVLNLTHNQLRRLPPTNFTRYSQL
AILDAGFNSISKLEPELCQILPLLKVLNLQHNELSQISDQTFVFCTNLTE
LDLMSNSIHKIKSNPFKNQKNLIKLDLSHNGLSSTKLGTGVQLENLQELL
LAKNKILALRSEELEFLGNSSLRKLDLSSNPLKEFSPGCFQTIGKLFALL
LNNAQLNPHLTEKLCWELSNTSIQNLSLANNQLLATSESTFSGLKWTNLT
QLDLSYNNLHDVGNGSFSYLPSLRYLSLEYNNIQRLSPRSFYGLSNLRYL
SLKRAFTKSHPNIDDFSFQWLKYLEYLNMDDNNIPSTKSNTFTGLVSLKY
LSLSKTFTSLQTLTNETFVSLAHSPLLTLNLTKNHISKIANGTFSWLGQL
RILDLGLNEIEQKLSGQEWRGLRNIFEIYLSYNKYLQLSTSSFALVPSLQ
RLMLRRVALKNVDISPSPFRPLRNLTILDLSNNNIANINEDLLEGLENLE
ILDFQHNNLARLWNPGGPVNFLKGLSHLHILNLESNGLDEIPVGVFKNLF
ELKSINLGLNNLNKLEPFIFDDQTSLRSLNLQKNLITSVEKDVFGPPFQN
LNSLDMRFNPFDCTCESISWFVNWINQTHTNISELSTHYLCNTPHHYYGF
PLKLFDTSSCK
3D structure
PDB3ciy Structural basis of toll-like receptor 3 signaling with double-stranded RNA.
ChainA
Resolution3.41 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 rna A H39 H60 F84 H108 A519 R544 K619 H12 H33 F57 H81 A486 R511 K583
BS02 rna A S86 S88 E110 N517 H539 N541 G573 S59 S61 E83 N484 H506 N508 G537
External links
PDB RCSB:3ciy, PDBe:3ciy, PDBj:3ciy
PDBsum3ciy
PubMed18420935
UniProtQ99MB1|TLR3_MOUSE Toll-like receptor 3 (Gene Name=Tlr3)

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