Structure of PDB 3cis Chain A

Receptor sequence

>3cisA (length=289) Species: 1773 (Mycobacterium tuberculosis) [Search protein sequence]

SSLGIIVGIDDSPAAQVAVRWAARDAELRKIPLTLVHAVSPEVATWLEVP
LPPGVLRWQQDHGRHLIDDALKVVEQASLRAGPPTVHSEIVPAAAVPTLV
DMSKDAVLMVVGCLGSGRWPGRLLGSVSSGLLRHAHCPVVIIHDEDSVMP
HPQQAPVLVGVDGSSASELATAIAFDEASRRNVDLVALHAWSDVDVSEWP
GIDWPATQSMAEQVLAERLAGWQERYPNVAITRVVVRDQPARQLVQRSEE
AQLVVVGSRGRGGYAGMLVGSVGETVAQLARTPVIVARE

3D structure

PDB

3cis The Crystal Structure of Rv2623 : a Novel, Tandem-Repeat Universal Stress Protein of Mycobacterium tuberculosis

Chain

Resolution

2.9 Å

3D
structure

[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]

Enzymatic activity

Enzyme Commision number

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	ATP	A	G13 I14 D15 A43 V116 G117 L119 G120 G122 R123 R127 G130 S131 V132	G8 I9 D10 A38 V111 G112 L114 G115 G117 R118 R122 G125 S126 V127
BS02	ATP	A	G165 V166 D167 S172 A195 P245 V261 G262 R264 G265 G267 G268 M272 G275 S276 V277	G160 V161 D162 S167 A190 P240 V256 G257 R259 G260 G262 G263 M267 G270 S271 V272

Gene Ontology

	Molecular Function
GO:0005524	ATP binding

	Biological Process
GO:0001666	response to hypoxia
GO:0040008	regulation of growth
GO:0085014	dormancy entry of symbiont in host

	Cellular Component
GO:0005829	cytosol
GO:0005886	plasma membrane
GO:0009274	peptidoglycan-based cell wall

View graph for
Molecular Function

View graph for
Biological Process

View graph for
Cellular Component

External links

PDB	RCSB:3cis, PDBe:3cis, PDBj:3cis
PDBsum	3cis
PubMed
UniProt	P9WFD7\|Y2623_MYCTU Universal stress protein Rv2623 (Gene Name=Rv2623)

[Back to BioLiP]