Structure of PDB 3cdz Chain A

Receptor sequence
>3cdzA (length=630) Species: 9606 (Homo sapiens) [Search protein sequence]
ATRRYYLGAVELSWDYVVYKKTLFVEFTDHLFNIAKPRPPWMGLLGPTIQ
AEVYDTVVITLKNMASHPVSLHAVGVSYWKASEGAEYDDQTSQREKEDDK
VFPGGSHTYVWQVLKENGPMASDPLCLTYSYLSHVDLVKDLNSGLIGALL
VCREGSLAKEKTQTLHKFILLFAVFDEGKSWHSSARAWPKMHTVNGYVNR
SLPGLIGCHRKSVYWHVIGMGTTPEVHSIFLEGHTFLVRNHRQASLEISP
ITFLTAQTLLMDLGQFLLFCHISSHQHDGMEAYVKVDSCPEEPKHPKTWV
HYIAAEEEDWDYAPLVLAPDDRSYKSQYLNNGPQRIGRKYKKVRFMAYTD
ETFKTREAIQHESGILGPLLYGEVGDTLLIIFKNQASRPYNIYPHGITDV
RPLYSRRLPKGVKHLKDFPILPGEIFKYKWTVTVEDGPTKSDPRCLTRYY
SSFVNMERDLASGLIGPLLICYKESVDQRGNQIMSDKRNVILFSVFDENR
SWYLTENIQRFLPNPAGVQLEDPEFQASNIMHSINGYVFDSLQLSVCLHE
VAYWYILSIGAQTDFLSVFFSGYTFKHKMVYEDTLTLFPFSGETVFMSME
NPGLWILGCHNSDFRNRGMTALLKVSSCDK
3D structure
PDB3cdz Crystal structure of human factor VIII: implications for the formation of the factor IXa-factor VIIIa complex.
ChainA
Resolution3.98 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 CU A H267 C310 H315 H227 C270 H275
BS02 CA A K107 D116 E122 D125 D126 K80 D89 E95 D98 D99
Gene Ontology
Molecular Function
GO:0005507 copper ion binding

View graph for
Molecular Function
External links
PDB RCSB:3cdz, PDBe:3cdz, PDBj:3cdz
PDBsum3cdz
PubMed18400180
UniProtP00451|FA8_HUMAN Coagulation factor VIII (Gene Name=F8)

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