Structure of PDB 3c94 Chain A
Receptor sequence
| >3c94A (length=458) Species: 562 (Escherichia coli) [Search protein sequence] |
| QQSTFLFHDYETFGTHPALDRPAQFAAIRTDSEFNVIGEPEVFYCKPADD YLPQPGAVLITGITPQEARAKGENEAAFAARIHSLFTVPKTCILGYNNVR FDDEVTRNIFYRNFYDPYAWSWQHDNSRWDLLDVMRACYALRPEGINWPE NDDGLPSFRLEHLTKANGIEHSDAMADVYATIAMAKLVKTRQPRLFDYLF THRNKHKLMALIDVPQMKPLVHVSGMFGAWRGNTSWVAPLAWHPENRNAV IMVDLAGDISPLLELDSDTLRERLYTAKTDLNAAVPVKLVHINKCPVLAQ ANTLRPEDADRLGINRQHCLDNLKILRENPQVREKVVAIFASDNVDAQLY NGFFSDADRAAMKIVLETEPRNLPALDITFVDKRIEKLLFNYRARNFPGT LDYAEQQRWLEHRRQVFTPEFLQGYADELQMLVQQYADDKEKVALLKALW QYADEIVE |
3D structure
| PDB | 3c94 Structural basis of Escherichia coli single-stranded DNA-binding protein stimulation of exonuclease I. | ||
| Chain | A | ||
| Resolution | 2.7 Å | ||
| 3D structure |
|
Enzymatic activity
| Enzyme Commision number | 3.1.11.1: exodeoxyribonuclease I. |
Interaction with ligand
| Site # |
Ligand | Ligand chain |
Binding residues on receptor (original residue number in PDB) |
Binding residues on receptor (residue number reindexed from 1) |
Binding affinity |
|---|---|---|---|---|---|
| BS01 | peptide | A | R148 L204 Y207 Q311 T314 | R142 L195 Y198 Q300 T303 | |
| BS02 | peptide | A | P228 W245 A312 R327 L331 | P219 W236 A301 R316 L320 | |
| BS03 | MG | A | E318 D319 | E307 D308 |
Gene Ontology
| Molecular Function | |
|---|---|
| GO:0000175 | 3'-5'-RNA exonuclease activity |
| GO:0000287 | magnesium ion binding |
| GO:0003676 | nucleic acid binding |
| GO:0003677 | DNA binding |
| GO:0003697 | single-stranded DNA binding |
| GO:0004527 | exonuclease activity |
| GO:0004529 | DNA exonuclease activity |
| GO:0005515 | protein binding |
| GO:0008310 | single-stranded DNA 3'-5' DNA exonuclease activity |
| GO:0046872 | metal ion binding |
| GO:0051575 | 5'-deoxyribose-5-phosphate lyase activity |
