Structure of PDB 3c5l Chain A

Receptor sequence
>3c5lA (length=217) Species: 9606 (Homo sapiens) [Search protein sequence]
HLSDMLQQLHSVNASKPSERGLVRQEEAEDPACIPIFWVSKWVDYSDKYG
LGYQLCDNSVGVLFNDSTRLILYNDGDSLQYIERDGTESYLTVSSHPNSL
MKKITLLKYFRNYMSEHLLKAGANITPREGRLPYLRTWFRTRSAIILHLS
NGSVQINFFQDHTKLILCPLMAAVTYIDEKRDFRTYRLSLLEEYGCCKEL
ASRLRYARTMVDKLLSS
3D structure
PDB3c5l Structural and functional analyses of minimal phosphopeptides targeting the polo-box domain of polo-like kinase 1.
ChainA
Resolution2.33 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.7.11.21: polo kinase.
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 peptide A K413 W414 D416 Y417 L490 L491 H538 K540 K41 W42 D44 Y45 L118 L119 H162 K164
External links
PDB RCSB:3c5l, PDBe:3c5l, PDBj:3c5l
PDBsum3c5l
PubMed19597481
UniProtP53350|PLK1_HUMAN Serine/threonine-protein kinase PLK1 (Gene Name=PLK1)

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