Structure of PDB 3c59 Chain A

Receptor sequence
>3c59A (length=103) Species: 9606 (Homo sapiens) [Search protein sequence]
TVSLWETVQKWREYRRQCQRSLTEDPPPATDLFCNRTFDEYACWPDGEPG
SFVNVSCPWYLPWASSVPQGHVYRFCTAEGLWLQKDNSSLPWRDLSECEE
SKR
3D structure
PDB3c59 Crystal Structure of the Ligand-bound Glucagon-like Peptide-1 Receptor Extracellular Domain
ChainA
Resolution2.3 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 peptide A V30 S31 L32 W39 E68 Y69 Y88 R121 E128 V2 S3 L4 W11 E40 Y41 Y60 R93 E100
BS02 10M A F80 N82 H99 Y101 F52 N54 H71 Y73
Gene Ontology
Molecular Function
GO:0004930 G protein-coupled receptor activity
GO:0004967 glucagon receptor activity
GO:0008528 G protein-coupled peptide receptor activity
Biological Process
GO:0007186 G protein-coupled receptor signaling pathway
Cellular Component
GO:0016020 membrane

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Molecular Function

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Biological Process

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Cellular Component
External links
PDB RCSB:3c59, PDBe:3c59, PDBj:3c59
PDBsum3c59
PubMed18287102
UniProtP43220|GLP1R_HUMAN Glucagon-like peptide 1 receptor (Gene Name=GLP1R)

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