Structure of PDB 3c2s Chain A

Receptor sequence
>3c2sA (length=210) Species: 9606 (Homo sapiens) [Search protein sequence]
GGPSVFLFPPKPKDTLMISRTPEVTCVVVDVSHEDPEVKFNWYVDGVEVH
NAKTKPREEQYNSTYRVVSVLTVLHQDWLNGKEYKCKVSNKALPASIEKT
ISKAKGQPREPQVYTLPPSREEMTKNQVSLTCLVKGFYPSDIAVEWESNG
QPENNYKTTPPVLDSDGSFFLYSKLTVDKSRWQQGNVFSCSVMHEALHNH
YTQKSLSLSP
3D structure
PDB3c2s Structural characterization of a human Fc fragment engineered for lack of effector functions.
ChainA
Resolution2.3 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 GAL A P244 K246 E258 T260 P9 K11 E23 T25
BS02 ZN A H310 H435 H75 H200
External links
PDB RCSB:3c2s, PDBe:3c2s, PDBj:3c2s
PDBsum3c2s
PubMed18560159
UniProtP01857|IGHG1_HUMAN Immunoglobulin heavy constant gamma 1 (Gene Name=IGHG1)

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