Structure of PDB 3c2i Chain A

Receptor sequence
>3c2iA (length=72) Species: 9606 (Homo sapiens) [Search protein sequence]
RGPMYDDPTLPEGWTRKLKQRKSGRSAGKYDVYLINPQGKAFRSKVELIM
YFEKVGDTSLDPNDFDFTVTGR
3D structure
PDB3c2i MeCP2 binding to DNA depends upon hydration at methyl-CpG
ChainA
Resolution2.5 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 dna A K109 R111 K112 S113 D121 R133 K19 R21 K22 S23 D31 R43
BS02 dna A K119 R133 S134 T158 V159 K29 R43 S44 T68 V69
Gene Ontology

View graph for
Molecular Function
External links
PDB RCSB:3c2i, PDBe:3c2i, PDBj:3c2i
PDBsum3c2i
PubMed18313390
UniProtP51608|MECP2_HUMAN Methyl-CpG-binding protein 2 (Gene Name=MECP2)

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