Structure of PDB 3c28 Chain A

Receptor sequence

>3c28A (length=299) Species: 2886926 (Escherichia phage P1) [Search protein sequence]

SDEVRKNLMDMFRDRQAFSEHTWKMLLSVCRSWAAWCKLNNRKWFPAEPE
DVRDYLLYLQARGLAVKTIQQHLGQLNMLHRRSGLPRPSDSNAVSLVMRR
IRKENVDAGERAKQALAFERTDFDQVRSLMENSDRCQDIRNLAFLGIAYN
TLLRIAEIARIRVKDIMLIHALSLGVTKLVERWISVSGVADDPNNYLFCR
VRKNGVAAPSATSQLSTRALEGIFEATHRLIYGAKDDGQRYLAWSGHSAR
VGAARDMARAGVSIPEIMQAGGWTNVNIVMNYIRNLDSETGAMVRLLED

3D structure

PDB

3c28 Detailed study on Synapsis in Cre-loxP recombination reaction

Chain

Resolution

2.6 Å

3D
structure

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Enzymatic activity

Enzyme Commision number

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	dna	A	F37 H40 T41 I174 A175 R243 K244 N245 R259 E262 K276 R282 Y283 S287 G288 H289	F18 H21 T22 I155 A156 R202 K203 N204 R218 E221 K235 R240 Y241 S245 G246 H247
BS02	dna	A	M44 S47 R50 R81 L83 K86 T87 H91 A131 K132 Q156 R159 R173 R241 V242 K244 L256 S257 A260 R282 Y283 W315 I320 Y324	M25 S28 R31 R62 L64 K67 T68 H72 A112 K113 Q137 R140 R154 R200 V201 K203 L215 S216 A219 R240 Y241 W273 I278 Y282

Gene Ontology

	Molecular Function
GO:0003677	DNA binding

	Biological Process
GO:0006310	DNA recombination
GO:0015074	DNA integration

View graph for
Molecular Function

View graph for
Biological Process

External links

PDB	RCSB:3c28, PDBe:3c28, PDBj:3c28
PDBsum	3c28
PubMed
UniProt	P06956\|RECR_BPP1 Recombinase cre (Gene Name=cre)

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