Structure of PDB 3c1s Chain A

Receptor sequence
>3c1sA (length=107) Species: 4932 (Saccharomyces cerevisiae) [Search protein sequence]
VSQETIKHVKDLIAENEIFVASKTYCPYCHAALNTLFEKLKVPRSKVLVL
QLNDMKEGADIQAALYEINGQRTVPNIYINGKHIGGNDDLQELRETGELE
ELLEPIL
3D structure
PDB3c1s Glutathionylation-triggered conformational changes of glutaredoxin Grx1 from the yeast Saccharomyces cerevisiae.
ChainA
Resolution2.5 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number 1.11.1.9: glutathione peroxidase.
2.5.1.18: glutathione transferase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 GSH A C27 Y29 Q63 T74 V75 G87 N88 D89 C26 Y28 Q62 T73 V74 G86 N87 D88
Gene Ontology
Molecular Function
GO:0004364 glutathione transferase activity
GO:0004602 glutathione peroxidase activity
GO:0005515 protein binding
GO:0015038 glutathione disulfide oxidoreductase activity
GO:0016491 oxidoreductase activity
GO:0016740 transferase activity
Biological Process
GO:0034599 cellular response to oxidative stress
GO:0098869 cellular oxidant detoxification
Cellular Component
GO:0005634 nucleus
GO:0005737 cytoplasm

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:3c1s, PDBe:3c1s, PDBj:3c1s
PDBsum3c1s
PubMed18473363
UniProtP25373|GLRX1_YEAST Glutaredoxin-1 (Gene Name=GRX1)

[Back to BioLiP]