Structure of PDB 3bzf Chain A

Receptor sequence
>3bzfA (length=276) Species: 9606 (Homo sapiens) [Search protein sequence]
GSHSLKYFHTSVSRPGRGEPRFISVGYVDDTQFVRFDNDAASPRMVPRAP
WMEQEGSEYWDRETRSARDTAQIFRVNLRTLRGYYNQSEAGSHTLQWMHG
CELGPDRRFLRGYEQFAYDGKDYLTLNEDLRSWTAVDTAAQISEQKSNDA
SEAEHQRAYLEDTCVEWLHKYLEKGKETLLHLEPPKTHVTHHPISDHEAT
LRCWALGFYPAEITLTWQQDGEGHTQDTELVETRPAGDGTFQKWAAVVVP
SGEEQRYTCHVQHEGLPEPVTLRWKP
3D structure
PDB3bzf Subtle changes in peptide conformation profoundly affect recognition of the non-classical MHC class I molecule HLA-E by the CD94-NKG2 natural killer cell receptors
ChainA
Resolution2.5 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide A Y7 E63 S66 A67 I73 N77 L81 Y84 W97 H99 W133 S143 K146 E152 Q156 Y159 W167 Y171 Y7 E63 S66 A67 I73 N77 L81 Y84 W97 H99 W133 S143 K146 E152 Q156 Y159 W167 Y171
External links
PDB RCSB:3bzf, PDBe:3bzf, PDBj:3bzf
PDBsum3bzf
PubMed18339401
UniProtP13747|HLAE_HUMAN HLA class I histocompatibility antigen, alpha chain E (Gene Name=HLA-E)

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