Structure of PDB 3bxf Chain A

Receptor sequence
>3bxfA (length=253) Species: 1423 (Bacillus subtilis) [Search protein sequence]
SNAKDVLGLTLLEKTLKERLNLKDAIIVSGDSDQSPWVKKEMGRAAVACM
KKRFSGKNIVAVTGGTTIEAVAEMMTPDSKNRELLFVPARGGLGEDVKNQ
ANTICAHMAEKASGTYRLLFVPGQLSQGAYSSIIEEPSVKEVLNTIKSAS
MLVHGIGEAKTMAQRRNTPLEDLKKIDDNDAVTEAFGYYFNADGEVVHKV
HSVGMQLDDIDAIPDIIAVAGGSSKAEAIEAYFKKPRNTVLVTDEGAAKK
LLR
3D structure
PDB3bxf Crystal structures of the effector-binding domain of repressor Central glycolytic gene Regulator from Bacillus subtilis reveal ligand-induced structural changes upon binding of several glycolytic intermediates.
ChainA
Resolution1.7 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 FBP A T148 G149 T151 T152 R175 Q185 G242 M247 R250 R251 E269 K310 T63 G64 T66 T67 R90 Q100 G157 M162 R165 R166 E184 K225 MOAD: Kd=2.87uM
PDBbind-CN: -logKd/Ki=5.54,Kd=2.87uM
Gene Ontology
Molecular Function
GO:0030246 carbohydrate binding

View graph for
Molecular Function
External links
PDB RCSB:3bxf, PDBe:3bxf, PDBj:3bxf
PDBsum3bxf
PubMed18554327
UniProtO32253|CGGR_BACSU Central glycolytic genes regulator (Gene Name=cggR)

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