Structure of PDB 3bus Chain A

Receptor sequence
>3busA (length=251) Species: 68170 (Lentzea aerocolonigenes) [Search protein sequence]
IWGENLHFGYWEDAGADVSVDDATDRLTDEMIALLDVRSGDRVLDVGCGI
GKPAVRLATARDVRVTGISISRPQVNQANARATAAGLANRVTFSYADAMD
LPFEDASFDAVWALESLHHMPDRGRALREMARVLRPGGTVAIADFVLLAP
VEGAKKEAVDAFRAGGGVLSLGGIDEYESDVRQAELVVTSTVDISAQARP
SLVKTAEAFENARSQVEPFMGAEGLDRMIATFRGLAEVPEAGYVLIGARK
P
3D structure
PDB3bus Structure and mechanism of the rebeccamycin sugar 4'-O-methyltransferase RebM.
ChainA
Resolution2.65 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.1.1.164: demethylrebeccamycin-D-glucose O-methyltransferase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 SAH A G69 P75 I92 Q96 D119 A120 L136 E137 H141 M142 G47 P53 I70 Q74 D97 A98 L114 E115 H119 M120
Gene Ontology
Molecular Function
GO:0008168 methyltransferase activity
GO:0008757 S-adenosylmethionine-dependent methyltransferase activity
GO:0102082 demethylrebeccamycin--D-glucose O-methyltransferase activity
Biological Process
GO:0032259 methylation

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Molecular Function
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Biological Process
External links
PDB RCSB:3bus, PDBe:3bus, PDBj:3bus
PDBsum3bus
PubMed18502766
UniProtQ8KZ94|REBMT_LENAE Demethylrebeccamycin-D-glucose O-methyltransferase (Gene Name=rebM)

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