Structure of PDB 3btz Chain A

Receptor sequence
>3btzA (length=202) Species: 9606 (Homo sapiens) [Search protein sequence]
WRHIRAEGLDSSYTVLFGKAEADEIFQELEKEVEYFTGALARVQVFGKWH
SVPRKQATYGDAGLTYTFSGLTLSPKPWIPVLERIRDHVSGVTGQTFNFV
LINRYKDGSDHIGEHRDDCRELAPGSPIASVSFGASRDFVFRHKDSRGKS
PSRRVAVVRLPLAHGSLLMMNHPTNTHWYHSLPVRKKVLAPRVNLTFRKI
LL
3D structure
PDB3btz Crystal structures of DNA/RNA repair enzymes AlkB and ABH2 bound to dsDNA.
ChainA
Resolution3.0 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 1.14.11.33: DNA oxidative demethylase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 dna A V101 F102 H106 P109 R110 Y122 F124 S125 H167 I168 G169 E170 H171 C175 R203 Y235 V45 F46 H50 P53 R54 Y66 F68 S69 H111 I112 G113 E114 H115 C119 R147 Y179
BS02 dna A F102 R176 R198 K205 R241 K242 F46 R120 R142 K149 R185 K186
Gene Ontology

View graph for
Biological Process
External links
PDB RCSB:3btz, PDBe:3btz, PDBj:3btz
PDBsum3btz
PubMed18432238
UniProtQ6NS38|ALKB2_HUMAN DNA oxidative demethylase ALKBH2 (Gene Name=ALKBH2)

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