Structure of PDB 3bty Chain A

Receptor sequence
>3btyA (length=200) Species: 9606 (Homo sapiens) [Search protein sequence]
SWRHIRAEGLDSSYTVLFGKAEADEIFQELEKEVEYFTGALARVQVFGKW
HSVPRKQATYGDAGLTYTFSGLTLSPKPWIPVLERIRDHVSGVTGQTFNF
VLINRYKDGSDHICEHRDDERELAPGSPIASVSFGASRDFVFRHKDSRPS
RRVAVVRLPLAHGSLLMMNHPTNTHWYHSLPVRKKVLAPRVNLTFRKILL
3D structure
PDB3bty Crystal structures of DNA/RNA repair enzymes AlkB and ABH2 bound to dsDNA.
ChainA
Resolution2.35 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 1.14.11.33: DNA oxidative demethylase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 dna A V101 F102 H106 R110 Y122 F124 S125 H167 I168 C169 H171 E175 Y235 V46 F47 H51 R55 Y67 F69 S70 H112 I113 C114 H116 E120 Y177
BS02 dna A F102 G103 K104 W105 R241 K242 F47 G48 K49 W50 R183 K184
Gene Ontology

View graph for
Biological Process
External links
PDB RCSB:3bty, PDBe:3bty, PDBj:3bty
PDBsum3bty
PubMed18432238
UniProtQ6NS38|ALKB2_HUMAN DNA oxidative demethylase ALKBH2 (Gene Name=ALKBH2)

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