Structure of PDB 3btc Chain A

Receptor sequence
>3btcA (length=186) Species: 158878 (Staphylococcus aureus subsp. aureus Mu50) [Search protein sequence]
NLKDKILGVAKELFIKNGYNATTTGEIVKLSESSKGNLYYHFKTKENLFL
EILNIQESKWQEQWKKEQIKAKTNREKFYLYNELSLTTEYYYPLQNAIIE
FYTEYYKTNSINEKMNKLENKYIDAYHVIFKEGNLNGEWSINDVNAVSKI
AANAVNGIVTFTHEQNINERIKLMNKFSQIFLNGLS
3D structure
PDB3btc QacR-cation recognition is mediated by a redundancy of residues capable of charge neutralization
ChainA
Resolution2.9 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 MGR A W61 E90 Y103 E120 Y123 I124 A153 N154 N157 W60 E89 Y102 E119 Y122 I123 A152 N153 N156 PDBbind-CN: -logKd/Ki=5.75,Kd=1.77uM
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0003700 DNA-binding transcription factor activity
Biological Process
GO:0045892 negative regulation of DNA-templated transcription

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Molecular Function
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Biological Process
External links
PDB RCSB:3btc, PDBe:3btc, PDBj:3btc
PDBsum3btc
PubMed18616285
UniProtP0A0N3|QACR_STAAM HTH-type transcriptional regulator QacR (Gene Name=qacR)

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