Structure of PDB 3bre Chain A

Receptor sequence
>3breA (length=322) Species: 208964 (Pseudomonas aeruginosa PAO1) [Search protein sequence]
AVMVLLVDDQAMIGEAVRRSLASEAGIDFHFCSDPQQAVAVANQIKPTVI
LQDLVMPGVDGLTLLAAYRGNPATRDIPIIVLSTKEEPTVKSAAFAAGAN
DYLVKLPDAIELVARIRYHSRSYIALQQRDEAYRALRESQQQLLETNLVL
QRLMNSDGLTGLSNRRHFDEYLEMEWRRSLREQSQLSLLMIDVDYFKSYN
DTFGHVAGDEALRQVAGAIREGCSRSSDLAARYGGEEFAMVLPGTSPGGA
RLLAEKVRRTVESLQISHDQPRPGSHLTVSIGVSTLVPGGGGQTFRVLIE
MADQALYQAKNNGRNQVGLMEQ
3D structure
PDB3bre Phosphorylation-independent regulation of the diguanylate cyclase WspR.
ChainA
Resolution2.4 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.7.7.65: diguanylate cyclase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 MG A D26 Q27 D70 D9 Q10 D53
BS02 C2E A R242 D245 L259 T262 G266 L270 R225 D228 L242 T245 G249 L253
BS03 C2E A S241 R242 S243 S224 R225 S226
Gene Ontology
Molecular Function
GO:0000166 nucleotide binding
GO:0042802 identical protein binding
GO:0046872 metal ion binding
GO:0052621 diguanylate cyclase activity
Biological Process
GO:0000160 phosphorelay signal transduction system
GO:0043709 cell adhesion involved in single-species biofilm formation
GO:1902201 negative regulation of bacterial-type flagellum-dependent cell motility
Cellular Component
GO:0005886 plasma membrane

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Cellular Component
External links
PDB RCSB:3bre, PDBe:3bre, PDBj:3bre
PDBsum3bre
PubMed18366254
UniProtQ9HXT9

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