Structure of PDB 3bli Chain A

Receptor sequence
>3bliA (length=311) Species: 173 (Leptospira interrogans) [Search protein sequence]
RLEILDVTLRDGEQTRGVSFSTSEKLNIAKFLLQKLNVDRVEIASARVSK
GELETVQKIMEWAATEQLTERIEILGFVDGNKTVDWIKDSGAKVLNLLTK
GSLHHLEKQLGKTPKEFFTDVSFVIEYAIKSGLKINVYLEDWSNGFRNSP
DYVKSLVEHLSKEHIERIFLPDTLGVLSPEETFQGVDSLIQKYPDIHFEF
HGHNDYDLSVANSLQAIRAGVKGLHASINGLGERAGNTPLEALVTTIHDK
SNSKTNINEIAITEASRLVEVFSGKRISANRPIVGEDVFTQTAGVNLYAN
PILPERFGRKR
3D structure
PDB3bli Molecular basis of the substrate specificity and the catalytic mechanism of citramalate synthase from Leptospira interrogans
ChainA
Resolution2.5 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) Q20
Catalytic site (residue number reindexed from 1) Q14
Enzyme Commision number 2.3.3.21: (R)-citramalate synthase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ZN A D17 H207 H209 D11 H201 H203
BS02 ACO A Q20 R53 V54 E146 Q14 R47 V48 E140
BS03 PYR A R16 Y144 P177 T179 R10 Y138 P171 T173
Gene Ontology
Molecular Function
GO:0003824 catalytic activity
GO:0046912 acyltransferase activity, acyl groups converted into alkyl on transfer
Biological Process
GO:0019752 carboxylic acid metabolic process

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Molecular Function
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Biological Process
External links
PDB RCSB:3bli, PDBe:3bli, PDBj:3bli
PDBsum3bli
PubMed18498255
UniProtQ8F3Q1|CIMA_LEPIN (R)-citramalate synthase CimA (Gene Name=cimA)

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