Structure of PDB 3bj7 Chain A

Receptor sequence
>3bj7A (length=162) Species: 10090 (Mus musculus) [Search protein sequence]
KFKIRPATASDCSDILRLIKELAKYEYMEDQVILTEKDLQEDGFGEHPFY
HCLVAEVPPEGHSIVGFAMYYFTYDPWIGKLLYLEDFFVMSDYRGFGIGS
EILKNLSQVAMKCRCSSMHFLVAEWNEPSINFYKRRGASDLSSEEGWRLF
KIDKEYLLKMAA
3D structure
PDB3bj7 The crystal structure of spermidine/spermine N1-acetyltransferase in complex with spermine provides insights into substrate binding and catalysis.
ChainA
Resolution2.2 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.3.1.57: diamine N-acetyltransferase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 COA A F94 F95 V96 R101 G102 F103 G104 G106 S107 F139 R142 R143 F87 F88 V89 R94 G95 F96 G97 G99 S100 F132 R135 R136
Gene Ontology
Molecular Function
GO:0004145 diamine N-acetyltransferase activity
GO:0008080 N-acetyltransferase activity
GO:0016746 acyltransferase activity
GO:0016747 acyltransferase activity, transferring groups other than amino-acyl groups
Biological Process
GO:0006596 polyamine biosynthetic process
GO:0009447 putrescine catabolic process
GO:0032918 spermidine acetylation
GO:0042127 regulation of cell population proliferation
GO:0046208 spermine catabolic process
Cellular Component
GO:0005737 cytoplasm
GO:0005829 cytosol

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Molecular Function
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Cellular Component
External links
PDB RCSB:3bj7, PDBe:3bj7, PDBj:3bj7
PDBsum3bj7
PubMed18690703
UniProtP48026|SAT1_MOUSE Diamine acetyltransferase 1 (Gene Name=Sat1)

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