Structure of PDB 3bc1 Chain A

Receptor sequence
>3bc1A (length=185) Species: 10090 (Mus musculus) [Search protein sequence]
GDYDYLIKFLALGDSGVGKTSVLYQYTDGKFNSKFITTVGIDFREKRVVY
RANGPDGAVGRGQRIHLQLWDTAGLERFRSLTTAFFRDAMGFLLLFDLTN
EQSFLNVRNWISQLQMHAYSENPDIVLCGNKSDLEDQRAVKEEEARELAE
KYGIPYFETSAANGTNISHAIEMLLDLIMKRMERS
3D structure
PDB3bc1 Elucidation of Rab27 recruitment by its effectors: structure of Rab27a bound to Exophilin4/Slp2-a
ChainA
Resolution1.8 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.6.5.2: small monomeric GTPase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 GNP A S18 G19 G21 K22 T23 S24 F34 S36 F38 T40 T41 G77 N133 K134 D136 L137 S163 A164 A165 S15 G16 G18 K19 T20 S21 F31 S33 F35 T37 T38 G74 N130 K131 D133 L134 S160 A161 A162
BS02 MG A T23 T41 T20 T38
Gene Ontology
Molecular Function
GO:0003924 GTPase activity
GO:0005525 GTP binding

View graph for
Molecular Function
External links
PDB RCSB:3bc1, PDBe:3bc1, PDBj:3bc1
PDBsum3bc1
PubMed18940603
UniProtQ9ERI2|RB27A_MOUSE Ras-related protein Rab-27A (Gene Name=Rab27a)

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