Structure of PDB 3bbr Chain A

Receptor sequence
>3bbrA (length=256) Species: 10116 (Rattus norvegicus) [Search protein sequence]
NKTVVVTTILESPYVMMKKNHEMLEGNERYEGYCVDLAAEIAKHCGFKYK
LTIVGDGKYGARDADTKIWNGMVGELVYGKADIAIAPLTITLVREEVIDF
SKPFMSLGISIMIKKGTPIESAEDLSKQTEIAYGTLDSGSTKEFFRRSKI
AVFDKMWTYMRSAEPSVFVRTTAEGVARVRKSKGKYAYLLESTMNEYIEQ
RKPCDTMKVGGNLDSKGYGIATPKGSSLGNAVNLAVLKLSEQGLLDKLKN
KWWYEC
3D structure
PDB3bbr Structural proof of a dimeric positive modulator bridging two identical AMPA receptor-binding sites
ChainA
Resolution2.25 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 GLU A Y61 L90 T91 R96 G141 S142 T143 E193 Y59 L88 T89 R94 G139 S140 T141 E191
BS02 BHY A P105 M107 S108 S217 K218 P103 M105 S106 S215 K216
Gene Ontology
Molecular Function
GO:0015276 ligand-gated monoatomic ion channel activity
Cellular Component
GO:0016020 membrane

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Molecular Function
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Cellular Component
External links
PDB RCSB:3bbr, PDBe:3bbr, PDBj:3bbr
PDBsum3bbr
PubMed18022568
UniProtP19491|GRIA2_RAT Glutamate receptor 2 (Gene Name=Gria2)

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