Structure of PDB 3bbp Chain A
Receptor sequence
>3bbpA (length=161) Species:
9606
(Homo sapiens) [
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FKLVFLGEQSVGKTSLITRFMYDSFDNTYQATIGIDFLSKTMYLEDRTVR
LQLWDTAGLERFRSLIPSYIRDSTVAVVVYDITNVNSFQQTTKWIDDVRT
ERGSDVIIMLVGNKTDLADKRQVSIEEGERKAKELNVMFIETSAKAGYNV
KQLFRRVAAAL
3D structure
PDB
3bbp
Rab and Arl GTPase family members cooperate in the localization of the golgin GCC185.
Chain
A
Resolution
3.0 Å
3D
structure
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Enzymatic activity
Enzyme Commision number
?
Interaction with ligand
Site
#
Ligand
Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01
MG
A
K26 T27 T45 D68
K13 T14 T32 D55
BS02
GTP
A
S23 V24 G25 K26 T27 S28 F38 N40 Y42 A44 T45 G71 K127 D129 L130 S156 K158
S10 V11 G12 K13 T14 S15 F25 N27 Y29 A31 T32 G58 K114 D116 L117 S143 K145
Gene Ontology
Molecular Function
GO:0003924
GTPase activity
GO:0005515
protein binding
GO:0005525
GTP binding
GO:0019904
protein domain specific binding
GO:0031489
myosin V binding
Biological Process
GO:0006886
intracellular protein transport
GO:0006890
retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum
GO:0006891
intra-Golgi vesicle-mediated transport
GO:0015031
protein transport
GO:0016192
vesicle-mediated transport
GO:0018125
peptidyl-cysteine methylation
GO:0019882
antigen processing and presentation
GO:0031175
neuron projection development
GO:0034067
protein localization to Golgi apparatus
GO:0034498
early endosome to Golgi transport
GO:0042147
retrograde transport, endosome to Golgi
GO:0072385
minus-end-directed organelle transport along microtubule
GO:1903292
protein localization to Golgi membrane
Cellular Component
GO:0000139
Golgi membrane
GO:0002080
acrosomal membrane
GO:0005789
endoplasmic reticulum membrane
GO:0005794
Golgi apparatus
GO:0005802
trans-Golgi network
GO:0005829
cytosol
GO:0005886
plasma membrane
GO:0012505
endomembrane system
GO:0016020
membrane
GO:0030667
secretory granule membrane
GO:0031410
cytoplasmic vesicle
GO:0032588
trans-Golgi network membrane
GO:0070062
extracellular exosome
GO:0070381
endosome to plasma membrane transport vesicle
View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB
RCSB:3bbp
,
PDBe:3bbp
,
PDBj:3bbp
PDBsum
3bbp
PubMed
18243103
UniProt
P20340
|RAB6A_HUMAN Ras-related protein Rab-6A (Gene Name=RAB6A)
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