Structure of PDB 3baz Chain A

Receptor sequence
>3bazA (length=311) Species: 4142 (Coleus scutellarioides) [Search protein sequence]
AIGVLMMCPMSTYLEQELDKRFKLFRYWTQPAQRDFLALQAESIRAVVGN
SNAGADAELIDALPKLEIVSSFSVGLDKVDLIKCEEKGVRVTNTPDVLTD
DVADLAIGLILAVLRRICECDKYVRRGAWKFGDFKLTTKFSGKRVGIIGL
GRIGLAVAERAEAFDCPISYFSRSKKPNTNYTYYGSVVELASNSDILVVA
CPLTPETTHIINREVIDALGPKGVLINIGRGPHVDEPELVSALVEGRLGG
AGLDVFEREPEVPEKLFGLENVVLLPHVGSGTVETRKVMADLVVGNLEAH
FSGKPLLTPVV
3D structure
PDB3baz Structure and substrate docking of a hydroxy(phenyl)pyruvate reductase from the higher plant Coleus blumei Benth
ChainA
Resolution2.2 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) L100 R232 A253 D256 E261 H279
Catalytic site (residue number reindexed from 1) L98 R230 A251 D254 E259 H277
Enzyme Commision number 1.1.1.237: hydroxyphenylpyruvate reductase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 NAP A V76 G151 L152 G153 R154 I155 S174 R175 S176 C203 P204 T209 I230 G231 R232 D256 H279 G281 V74 G149 L150 G151 R152 I153 S172 R173 S174 C201 P202 T207 I228 G229 R230 D254 H277 G279
Gene Ontology
Molecular Function
GO:0000166 nucleotide binding
GO:0016491 oxidoreductase activity
GO:0016616 oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
GO:0016618 hydroxypyruvate reductase [NAD(P)H] activity
GO:0030267 glyoxylate reductase (NADPH) activity
GO:0047995 hydroxyphenylpyruvate reductase activity
GO:0051287 NAD binding
Cellular Component
GO:0005829 cytosol

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Molecular Function
View graph for
Cellular Component
External links
PDB RCSB:3baz, PDBe:3baz, PDBj:3baz
PDBsum3baz
PubMed20445235
UniProtQ65CJ7|HPPR_PLESU Hydroxyphenylpyruvate reductase (Gene Name=HPPR)

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