Structure of PDB 3b7v Chain A

Receptor sequence
>3b7vA (length=99) Species: 11678 (Human immunodeficiency virus type 1 BH10) [Search protein sequence]
PQITLWKRPLVTIKIGGQLKEALLDTGADDTVIEEMSLPGRWKPKMIGGI
GGFIKVRQYDQIIIEIAGHKAIGTVLVGPTPVNIIGRNLLTQIGATLNF
3D structure
PDB3b7v Caught in the Act: The 1.5 A Resolution Crystal Structures of the HIV-1 Protease and the I54V Mutant Reveal a Tetrahedral Reaction Intermediate.
ChainA
Resolution1.46 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.4.23.16: HIV-1 retropepsin.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide A R8 D25 G27 A28 D29 D30 I47 G48 G49 R8 D25 G27 A28 D29 D30 I47 G48 G49
Gene Ontology
Molecular Function
GO:0004190 aspartic-type endopeptidase activity
GO:0042802 identical protein binding
Biological Process
GO:0006508 proteolysis

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Molecular Function
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Biological Process
External links
PDB RCSB:3b7v, PDBe:3b7v, PDBj:3b7v
PDBsum3b7v
PubMed18052235
UniProtQ7SSI0

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