Structure of PDB 3b7k Chain A

Receptor sequence
>3b7kA (length=267) Species: 9606 (Homo sapiens) [Search protein sequence]
SMGEVVMSQAIQPAHATARGELSAGQLLKWIDTTACLAAEKHAGVSCVTA
SVDDIQFEETARVGQVITIKAKVTRAFSTSMEISIKVMVQDMLTGIEKLV
SVAFSTFVAKPVGKIHLKPVTLLTEQDHVEHNLAAERRKVRLQHEDTRGT
SVQSIELVLPPHANHHGNTFGGQIMAWMETVATISASRLCWAHPFLKSVD
MFKFRGPSTVGDRLVFTAIVNNTFQTCVEVGVRVEAFDCQEWAEGRGRHI
NSAFLIYNAADDKENLI
3D structure
PDB3b7k Human Acyl-coenzyme A thioesterase 12.
ChainA
Resolution2.7 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.1.2.1: acetyl-CoA hydrolase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 COA A V52 T53 S55 S82 T83 S84 T110 R144 L148 F235 R236 G237 V48 T49 S51 S78 T79 S80 T106 R138 L142 F204 R205 G206
Gene Ontology
Molecular Function
GO:0016790 thiolester hydrolase activity

View graph for
Molecular Function
External links
PDB RCSB:3b7k, PDBe:3b7k, PDBj:3b7k
PDBsum3b7k
PubMed
UniProtQ8WYK0|ACO12_HUMAN Acetyl-coenzyme A thioesterase (Gene Name=ACOT12)

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