Structure of PDB 3b6w Chain A

Receptor sequence
>3b6wA (length=258) Species: 10116 (Rattus norvegicus) [Search protein sequence]
KTVVVTTILESPYVMMKKNHEMLEGNERYEGYCVDLAAEIAKHCGFKYKL
TIVGDGKYGARDADTKIWNGMVGELVYGKADIAIAPLTITLVREEVIDFS
KPFMSLGISIMIKKGTPIESAEDLSKQTEIAYGTLDSGSTKEFFRRSKIA
VFDKMWTYMRSAEPSVFVRTSAEGVARVRKSKGKYAYLLESTMNEYIEQR
KPCDTMKVGGNLDSKGYGIATPKGSSLGNAVNLAVLKLNEQGLLDKLKNK
WWYDKGEC
3D structure
PDB3b6w Structural and single-channel results indicate that the rates of ligand binding domain closing and opening directly impact AMPA receptor gating.
ChainA
Resolution1.7 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 GLU A Y450 L479 T480 R485 G653 S654 T655 E705 Y58 L87 T88 R93 G138 S139 T140 E190
Gene Ontology
Molecular Function
GO:0015276 ligand-gated monoatomic ion channel activity
Cellular Component
GO:0016020 membrane

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Molecular Function
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Cellular Component
External links
PDB RCSB:3b6w, PDBe:3b6w, PDBj:3b6w
PDBsum3b6w
PubMed18216201
UniProtP19491|GRIA2_RAT Glutamate receptor 2 (Gene Name=Gria2)

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