Structure of PDB 3b67 Chain A

Receptor sequence
>3b67A (length=247) Species: 9606 (Homo sapiens) [Search protein sequence]
PIFLNVLEAIEPGVVCAGHDNNQPDSFAALLSSLNELGERQLVHVVKWAK
ALPGFRNLHVDDQMAVIQYSWMGLMVFAMGWRSFTNVNSRMLYFAPDLVF
NEYRMHKSRMYSQCVRMRHLSQEFGWLQITPQEFLCMKALLLFSIIPVDG
LKNQKFFDELRMNYIKELDRIIACKRKNPTSCSRRFYQLTKLLDSVQPIA
RELHQFTFDLLIKSHMVSVDFPEMMAEIISVQVPKILSGKVKPIYFH
3D structure
PDB3b67 Effect of B-ring substitution pattern on binding mode of propionamide selective androgen receptor modulators
ChainA
Resolution1.9 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 B67 A L704 N705 Q711 W741 M742 M745 V746 M749 F764 T877 M895 I899 L34 N35 Q41 W71 M72 M75 V76 M79 F94 T207 M225 I229 PDBbind-CN: -logKd/Ki=8.85,Ki=1.4nM
External links
PDB RCSB:3b67, PDBe:3b67, PDBj:3b67
PDBsum3b67
PubMed18805694
UniProtP10275|ANDR_HUMAN Androgen receptor (Gene Name=AR)

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