Structure of PDB 3b1m Chain A

Receptor sequence
>3b1mA (length=260) Species: 9606 (Homo sapiens) [Search protein sequence]
PESADLRALAKHLYDSYIKSFPLTKAKARAILTGKTTDKSPFVIYDMNSL
MMGEDKIKEVAIRIFQGCQFRSVEAVQEITEYAKSIPGFVNLDLNDQVTL
LKYGVHEIIYTMLASLMNKDGVLISEGQGFMTREFLKSLRKPFGDFMEPK
FEFAVKFNALELDDSDLAIFIAVIILSGDRPGLLNVKPIEDIQDNLLQAL
ELQLKLNHPESSQLFAKLLQKMTDLRQIVTEHVQLLQVIKKTETDMSLHP
LLQEIYKDLY
3D structure
PDB3b1m Pharmacology and in Vitro Profiling of a Novel Peroxisome Proliferator-Activated Receptor gamma Ligand, Cerco-A
ChainA
Resolution1.6 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide A K301 L311 N312 Q314 V315 L318 L468 E471 K84 L94 N95 Q97 V98 L101 L251 E254
BS02 KRC A G284 C285 F287 R288 S289 L330 M334 I341 L353 M364 K367 G67 C68 F70 R71 S72 L113 M117 I124 L136 M147 K150 MOAD: Ki=3.3nM
PDBbind-CN: -logKd/Ki=8.48,Ki=3.3nM
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0004879 nuclear receptor activity
Biological Process
GO:0006355 regulation of DNA-templated transcription
Cellular Component
GO:0005634 nucleus

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Cellular Component
External links
PDB RCSB:3b1m, PDBe:3b1m, PDBj:3b1m
PDBsum3b1m
PubMed21720019
UniProtP37231|PPARG_HUMAN Peroxisome proliferator-activated receptor gamma (Gene Name=PPARG)

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