Structure of PDB 3b0x Chain A

Receptor sequence
>3b0xA (length=575) Species: 300852 (Thermus thermophilus HB8) [Search protein sequence]
MRNQELARIFEEIGLMSEFLGDNPFRVRAYHQAARTLYDLDTPIEEIAEK
GKEALMELPGVGPDLAEKILEFLRTGKVRKHEELSRKVPRGVLEVMEVPG
VGPKTARLLYEGLGIDSLEKLKAALDRGDLTRLKGFGPKRAERIREGLAL
AQAAGKRRPLGAVLSLARSLLEAIRALPGVERAELCGSARRYKDTVGDLD
FLVASREGERAVEGFVRLPQVKEVYAKGKERATVFLKNGLQVDLRVVPPE
SYGAGLQYLTGSAAHSIRLRALAQEKGLKLSEYGVFRGEKRIAGETEEEV
YAALGLPWIPPPLREDQGEVEAALEGRLPKLLELPQVKGDLQVHSTYSDG
QNTLEELWEAAKTMGYRYLAVTDHSPAVRVAGGPSPEEALKRVGEIRRFN
ETHGPPYLLAGAEVDIHPDGTLDYPDWVLRELDLVLVSVHSRFNLPKADQ
TKRLLKALENPFVHVLAHPTARLLGRRAPIEADWEAVFQKAKEKGVAVEI
DGYYDRMDLPDDLARMAYGMGLWISLSTDAHQTDHLRFMELAVGTAQRAW
IGPERVLNTLDYEDLLSWLKARRGV
3D structure
PDB3b0x The structural basis of the kinetic mechanism of a gap-filling X-family DNA polymerase that binds Mg(2+)-dNTP before binding to DNA.
ChainA
Resolution1.36 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.7.7.7: DNA-directed DNA polymerase.
4.2.99.18: DNA-(apurinic or apyrimidinic site) lyase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ZN A D349 H374 H531 D349 H374 H531
BS02 ZN A E413 H440 H468 E413 H440 H468
BS03 CA A D198 D200 D198 D200
BS04 CA A D198 D200 D243 D198 D200 D243
BS05 CA A R175 A176 L177 V180 R175 A176 L177 V180
BS06 CA A M56 L58 V61 M56 L58 V61
BS07 DGT A R157 G187 S188 R191 G197 D200 Y258 T260 G261 R157 G187 S188 R191 G197 D200 Y258 T260 G261
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0003824 catalytic activity
GO:0003887 DNA-directed DNA polymerase activity
GO:0008270 zinc ion binding
GO:0042578 phosphoric ester hydrolase activity
GO:0046872 metal ion binding
Biological Process
GO:0006259 DNA metabolic process
GO:0006281 DNA repair
GO:0071897 DNA biosynthetic process
GO:0071978 bacterial-type flagellum-dependent swarming motility
Cellular Component
GO:0005737 cytoplasm
GO:0005829 cytosol

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:3b0x, PDBe:3b0x, PDBj:3b0x
PDBsum3b0x
PubMed22306405
UniProtQ5SJ64

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