Structure of PDB 3aye Chain A

Receptor sequence
>3ayeA (length=135) Species: 9606 (Homo sapiens) [Search protein sequence]
MPYNLPLPGGVVPRMLITILGTVKPNANRIALDFQRGNDVAFHFNPRFNE
NNRRVIVCNTKLDNNWGREERQSVFPFESGKPFKIQVLVEPDHFKVAVND
AHLLQYNHRVKKLNEISKLGISGDIDLTSASYTMI
3D structure
PDB3aye Structural basis for distinct binding properties of the human galectins to thomsen-friedenreich antigen
ChainA
Resolution2.0 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 BGC A R162 E184 R186 R47 E69 R71
BS02 GAL A H158 R162 N174 W181 E184 H43 R47 N59 W66 E69
Gene Ontology
Molecular Function
GO:0030246 carbohydrate binding

View graph for
Molecular Function
External links
PDB RCSB:3aye, PDBe:3aye, PDBj:3aye
PDBsum3aye
PubMed21949831
UniProtP17931|LEG3_HUMAN Galectin-3 (Gene Name=LGALS3)

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