Structure of PDB 3aya Chain A

Receptor sequence
>3ayaA (length=135) Species: 9606 (Homo sapiens) [Search protein sequence]
MPYNLPLPGGVVPRMLITILGTVKPNANRIALDFQRGNDVAFHFNPRFNE
NNRRVIVCNTKLDNNWGREERQSVFPFESGKPFKIQVLVEPDHFKVAVND
AHLLQYNHRVKKLNEISKLGISGDIDLTSASYTMI
3D structure
PDB3aya Structural basis for distinct binding properties of the human galectins to thomsen-friedenreich antigen
ChainA
Resolution2.0 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 GAL A H158 R162 W181 E184 H43 R47 W66 E69 PDBbind-CN: -logKd/Ki=4.33,Kd=47uM
Gene Ontology
Molecular Function
GO:0030246 carbohydrate binding

View graph for
Molecular Function
External links
PDB RCSB:3aya, PDBe:3aya, PDBj:3aya
PDBsum3aya
PubMed21949831
UniProtP17931|LEG3_HUMAN Galectin-3 (Gene Name=LGALS3)

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