Structure of PDB 3asl Chain A

Receptor sequence
>3aslA (length=68) Species: 9606 (Homo sapiens) [Search protein sequence]
GPSCKHCKDDVNRLCRVCACHLCGGRQDPDKQLMCDECDMAFHIYCLDPP
LSSVPSEDEWYCPECRND
3D structure
PDB3asl Recognition of modification status on a histone H3 tail by linked histone reader modules of the epigenetic regulator UHRF1
ChainA
Resolution1.41 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.3.2.27: RING-type E3 ubiquitin transferase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide A C316 P327 D328 Q330 L331 M332 C333 D334 D337 V352 P353 E355 C18 P29 D30 Q32 L33 M34 C35 D36 D39 V54 P55 E57
BS02 ZN A C302 C305 C313 C316 C4 C7 C15 C18
BS03 ZN A C318 C321 H341 C344 C20 C23 H43 C46
BS04 ZN A C333 C336 C360 C363 C35 C38 C62 C65
BS05 ZN A H319 E362 H21 E64
External links
PDB RCSB:3asl, PDBe:3asl, PDBj:3asl
PDBsum3asl
PubMed22837395
UniProtQ96T88|UHRF1_HUMAN E3 ubiquitin-protein ligase UHRF1 (Gene Name=UHRF1)

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