Structure of PDB 3ano Chain A

Receptor sequence
>3anoA (length=158) Species: 83332 (Mycobacterium tuberculosis H37Rv) [Search protein sequence]
HTIFDRGVGQRDQLQRLWTPYRAQPFTEIPQLSDEEGLVVARGKLVYAVL
NLYPYNPGHLMVVPYRRVSELEDLTDLESAELMAFTQKAIRVIKNVSRPH
GFNVGLNLGTSAGGSLAEHLHVHVVPRWGGDANFITIIIPQLLRDTRRLL
ATEWARQP
3D structure
PDB3ano Structural insights into the novel diadenosine 5',5-P1,P4-tetraphosphate phosphorylase from Mycobacterium tuberculosis H37Rv
ChainA
Resolution1.894 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) N139 H151 H153 H155
Catalytic site (residue number reindexed from 1) N107 H119 H121 H123
Enzyme Commision number 2.7.7.53: ATP adenylyltransferase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 PO4 A N139 G146 S147 L148 H153 H155 N107 G114 S115 L116 H121 H123
Gene Ontology
Molecular Function
GO:0003824 catalytic activity
GO:0003877 ATP:ADP adenylyltransferase activity
GO:0005524 ATP binding
GO:0008796 bis(5'-nucleosyl)-tetraphosphatase activity
GO:0016779 nucleotidyltransferase activity
Biological Process
GO:0015967 diadenosine tetraphosphate catabolic process
Cellular Component
GO:0005886 plasma membrane

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External links
PDB RCSB:3ano, PDBe:3ano, PDBj:3ano
PDBsum3ano
PubMed21565198
UniProtP9WMK9|AP4A_MYCTU AP-4-A phosphorylase (Gene Name=Rv2613c)

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