Structure of PDB 3al3 Chain A

Receptor sequence
>3al3A (length=218) Species: 9606 (Homo sapiens) [Search protein sequence]
KQYIFQLSSLNPQERIDYCHLIEKLGGLVIEKQCFDPTCTHIVVGHPLRN
EKYLASVAAGKWVLHRSYLEACRTAGHFVQEEDYEWGSSSILDVLTGINV
QQRRLALAAMRWRKKIQQRQESGIVEGAFSGWKVILHVDQSREAGFKRLL
QSGGAKVLPGHSVPLFKEATHLFSDLGVNIAEAAAQNVYCLRTEYIADYL
MQESPPHVENYCLPEAIS
3D structure
PDB3al3 Molecular basis of BACH1/FANCJ recognition by TopBP1 in DNA replication checkpoint control
ChainA
Resolution2.15 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide A S1273 S1274 L1275 P1277 R1280 H1311 L1313 R1314 N1315 K1317 R1407 F1411 T1466 E1467 A1470 S8 S9 L10 P12 R15 H46 L48 R49 N50 K52 R142 F146 T193 E194 A197
External links
PDB RCSB:3al3, PDBe:3al3, PDBj:3al3
PDBsum3al3
PubMed21127055
UniProtQ92547|TOPB1_HUMAN DNA topoisomerase 2-binding protein 1 (Gene Name=TOPBP1)

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