Structure of PDB 3aje Chain A

Receptor sequence
>3ajeA (length=329) Species: 273063 (Sulfurisphaera tokodaii str. 7) [Search protein sequence]
TQIIKIDPLNPEIDKIKIAADVIRNGGTVAFPTETVYGLGANAFDGNACL
KIFQAKNRPVDNPLIVHIADFNQLFEVAKDIPDKVLEIAQIVWPGPLTFV
LKKTERVPKEVTAGLDTVAVRMPAHPIALQLIRESGVPIAAPSANLATRP
SPTKAEDVIVDLNGRVDVIIDGGHTFFGVESTIINVTVEPPVLLRPGPFT
IEELKKLFGEIVIPHYAPNTRLLLVENRNIFKDVVSLLSKKYKVALLIPK
ELSKEFEGLQQIILGSDENLYEVARNLFDSFRELDKLNVDLGIMIGFPER
GIGFAIMNRARKASGFSIIKAISDVYKYV
3D structure
PDB3aje Crystal structure of Sulfolobus tokodaii Sua5 complexed with L-threonine and AMPPNP
ChainA
Resolution1.8 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.7.7.87: L-threonylcarbamoyladenylate synthase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 THR A T36 V37 G39 H68 R122 A142 E181 S182 T35 V36 G38 H67 R121 A141 E180 S181 PDBbind-CN: -logKd/Ki=5.03,Kd=9.3uM
BS02 ANP A R59 N63 P64 I66 T118 A120 P143 S144 E181 I184 R196 Y237 R58 N62 P63 I65 T117 A119 P142 S143 E180 I183 R195 Y216
Gene Ontology
Molecular Function
GO:0000049 tRNA binding
GO:0003725 double-stranded RNA binding
GO:0005524 ATP binding
GO:0016779 nucleotidyltransferase activity
GO:0061710 L-threonylcarbamoyladenylate synthase
Biological Process
GO:0006450 regulation of translational fidelity
GO:0008033 tRNA processing
Cellular Component
GO:0005737 cytoplasm

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:3aje, PDBe:3aje, PDBj:3aje
PDBsum3aje
PubMed21538543
UniProtQ970S6|SUA5_SULTO Threonylcarbamoyl-AMP synthase (Gene Name=sua5)

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