Structure of PDB 3aii Chain A

Receptor sequence
>3aiiA (length=455) Species: 187420 (Methanothermobacter thermautotrophicus str. Delta H) [Search protein sequence]
LRELAGVKGEVVLRFAPNPSGPLHIGHARAAILNHEYARKYDGRLILRIE
DTDPRRVDPEAYDMIPADLEWLGVEWDETVIQSDRMETYYEYTEKLIERG
GAYVCTCRPEEFRELKNRGEACHCRSLGFRENLQRWREMFEMKEGSAVVR
VKTDLNHPNPAIRDWVSMRIVEAEHPRTGTRYRVYPMMNFSVAVDDHLLG
VTHVLRANREKQEYLYRHLGWEPPEFIHYGRLKTSGAREGILRGEYSGWD
DPRLGTLRAIARRGIRPEAIRKLMVEIGVKIADSTMSWKKIYGLNRSILE
EEARRYFFAADPVKLEVVGLPGPVRVERPLHPDHPEIGNRVLELRGEVYL
PGDDLGEGPLRLIDAVNVIYSGGELRYHSEGIEEARELGASMIHWVPAES
ALEAEVIMPDASRVRGVIEADASELEVDDVVQLERFGFARLDSAGPGMVF
YYAHK
3D structure
PDB3aii Structure of an archaeal non-discriminating glutamyl-tRNA synthetase: a missing link in the evolution of Gln-tRNAGln formation
ChainA
Resolution1.65 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) N104 R322 T332
Catalytic site (residue number reindexed from 1) N18 R231 T234
Enzyme Commision number 6.1.1.17: glutamate--tRNA ligase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ZN A C191 C193 C208 C210 C105 C107 C122 C124
Gene Ontology
Molecular Function
GO:0000166 nucleotide binding
GO:0004812 aminoacyl-tRNA ligase activity
GO:0004818 glutamate-tRNA ligase activity
GO:0005524 ATP binding
Biological Process
GO:0006412 translation
GO:0006418 tRNA aminoacylation for protein translation
GO:0006424 glutamyl-tRNA aminoacylation
GO:0043039 tRNA aminoacylation
GO:0043604 amide biosynthetic process
Cellular Component
GO:0005737 cytoplasm
GO:0005829 cytosol

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:3aii, PDBe:3aii, PDBj:3aii
PDBsum3aii
PubMed20601684
UniProtO26157|SYE_METTH Glutamate--tRNA ligase (Gene Name=gltX)

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