Structure of PDB 3adb Chain A

Receptor sequence
>3adbA (length=250) Species: 243232 (Methanocaldococcus jannaschii DSM 2661) [Search protein sequence]
HHMLIILTGLPGVGKSTFSKNLAKILSKNNIDVIVLGSDLIRESFPVWKE
KYEEFIKKSTYRLIDSALKNYWVIVDDTNYYNSMRRDLINIAKKYNKNYA
IIYLKASLDVLIRRNIERGEKIPNEVIKKMYEKFDEPGKKYKWDEPFLII
DTTKDIDFNEIAKKLIEKSKEIPKFYVLEENKNKNNNISDKIDKETRKIV
SEYIKSKKLDKDKIKEVVELRKEFLKKIKKMEEVDADRVLKEFKDLLNSY
3D structure
PDB3adb Structural Basis for the Major Role of O-Phosphoseryl-tRNA Kinase in the UGA-Specific Encoding of Selenocysteine
ChainA
Resolution2.8 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.7.1.164: O-phosphoseryl-tRNA(Sec) kinase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 rna A Y79 K91 I120 V124 M128 K138 N181 D191 R195 S199 I202 K203 K209 I212 V216 R219 K220 K224 K227 Y81 K93 I122 V126 M130 K140 N183 D193 R197 S201 I204 K205 K211 I214 V218 R221 K222 K226 K229 PDBbind-CN: Kd=39nM
BS02 PO4 A G10 V11 G12 K13 S14 R116 G12 V13 G14 K15 S16 R118
Gene Ontology
Molecular Function
GO:0005524 ATP binding
GO:0016301 kinase activity
GO:0016773 phosphotransferase activity, alcohol group as acceptor
GO:0043915 L-seryl-tRNA(Sec) kinase activity
Biological Process
GO:0001717 conversion of seryl-tRNAsec to selenocys-tRNAsec
GO:0002098 tRNA wobble uridine modification
GO:0016310 phosphorylation

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Molecular Function
View graph for
Biological Process
External links
PDB RCSB:3adb, PDBe:3adb, PDBj:3adb
PDBsum3adb
PubMed20705242
UniProtQ58933|PSTK_METJA L-seryl-tRNA(Sec) kinase (Gene Name=pstK)

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