Structure of PDB 3a9v Chain A

Receptor sequence
>3a9vA (length=528) Species: 118781 (Populus tomentosa) [Search protein sequence]
EEFIFRSKLPDIYIPKNLPLHSYVLENLSNHSSKPCLINGANGDVYTYAD
VELTARRVASGLNKIGIQQGDVIMLFLPSSPEFVLAFLGASHRGAIITAA
NPFSTPAELAKHAKASRAKLLITQACYYEKVKDFARESDVKVMCVDSAPD
GCLHFSELTQADENEAPQVDISPDDVVALPYSSGTTGLPKGVMLTHKGLI
TSVAQQVDGDNPNLYFHSEDVILCVLPMFHIYALNSIMLCGLRVGAPILI
MPKFEIGSLLGLIEKYKVSIAPVVPPVMMSIAKSPDLDKHDLSSLRMIKS
GGAPLGKELEDTVRAKFPQARLGQGYGMTEAGPVLAMCLAFAKEPFDIKP
GACGTVVRNAEMKIVDPETGASLPRNQPGEICIRGDQIMKGYLNDPEATS
RTIDKEGWLHTGDIGYIDDDDELFIVDRLKELIKYKGFQVAPAELEALLI
AHPEISDAAVVGLKDEDAGEVPVAFVVKSEKSQATEDEIKQYISKQVIFY
KRIKRVFFIEAIPKAPSGKILRKNLKEK
3D structure
PDB3a9v Crystal structures of a Populus tomentosa 4-coumarate:CoA ligase shed light on its enzymatic mechanisms
ChainA
Resolution2.5 Å
3D
structure
Catalytic site residues are labeled in the structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Catalytic site (original residue number in PDB) S186 S206 H234 T333 E334 K438 Q443 K523
Catalytic site (residue number reindexed from 1) S182 S202 H230 T329 E330 K434 Q439 K519
Enzyme Commision number 6.2.1.12: 4-coumarate--CoA ligase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 AMP A H234 G306 A307 P308 Y330 G331 M332 T333 D417 K434 K438 Q443 H230 G302 A303 P304 Y326 G327 M328 T329 D413 K430 K434 Q439
Gene Ontology
Molecular Function
GO:0000166 nucleotide binding
GO:0003824 catalytic activity
GO:0016405 CoA-ligase activity
GO:0016874 ligase activity

View graph for
Molecular Function
External links
PDB RCSB:3a9v, PDBe:3a9v, PDBj:3a9v
PDBsum3a9v
PubMed20841425
UniProtQ941M3

[Back to BioLiP]