Structure of PDB 3a9e Chain A

Receptor sequence
>3a9eA (length=218) Species: 10090 (Mus musculus) [Search protein sequence]
SANEDMPVEKILEAELAVEPKSPNDPVTNICQAADKQLFTLVEWAKRIPH
FSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAH
SAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAE
VEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFF
FKLIGDTPIDTFLMEMLE
3D structure
PDB3a9e The Phantom Effect of the Rexinoid LG100754: structural and functional insights
ChainA
Resolution2.75 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 754 A I273 A276 A277 W310 F318 R321 L331 A332 C437 I30 A33 A34 W67 F75 R78 L88 A89 C194
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0003707 nuclear steroid receptor activity
GO:0008270 zinc ion binding
Biological Process
GO:0006355 regulation of DNA-templated transcription
Cellular Component
GO:0005634 nucleus

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:3a9e, PDBe:3a9e, PDBj:3a9e
PDBsum3a9e
PubMed21152046
UniProtP28700|RXRA_MOUSE Retinoic acid receptor RXR-alpha (Gene Name=Rxra)

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