Structure of PDB 3a7q Chain A

Receptor sequence
>3a7qA (length=685) Species: 10090 (Mus musculus) [Search protein sequence]
NNPVLLLDTFDFGPREDNWFFYPGGNIGLYCPYSDSAMVFVSNEVGEHSI
TTRDLSVNENTIIQFEINVGCSTDSSSADPVRLEFSRDFGATWHLLLPLC
HHPSSTYYAGTTQGWRREVVHFGKLHLAGSVRFRWYQGFYPAGSQPVTWA
IDNVYIGPQCEEMCYGHGSCINGTKCICDPGYSGPTCKISTKNPDFLKDD
FEGDRFLLMSGGKPSRKCGILSSGNNLFFNEDGLRMLVTRDLDLSHARFV
QFFMRLGCGKGVPDPRSQPVLLQYSLNGGLSWSLLQEFLFSNSSNVGRYI
ALEMPLKARSGSTRLRWWQPSENGHFYSPWVIDQILIGGNISGNTVLEDD
FSTLDSRKWLLHPGGTKMPVCGSTGDALVFIEKASTRYVVTTDIAVNEDS
FLQIDFAASCSVTDSCYAIELEYSVDLGLSWHPLVRDCLPTNVECSRYHL
QRILVSDTFNKWTRITLPLPSYTRSQATRFRWHQPAPFDKQQTWAIDNVY
IGDGCLDMCSGHGRCVQGSCVCDEQWGGLYCDEPETSLPTQLKDNFNRAP
SNQNWLTVSGGKLSTVCGAVASGLALHFSGGCSRLLVTVDLNLTNAEFIQ
FYFMYGCLITPSNRNQGVLLEYSVNGGITWNLLMEIFYDQYSKPGFVNIL
LPPDAKEIATRFRWWQPRHDGLDQNDWAIDNVLIS
3D structure
PDB3a7q Structural Basis for Specific Recognition of Reelin by Its Receptors
ChainA
Resolution2.6 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.4.21.-
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 CA A T1961 D1963 S1995 D2125 T9 D11 S36 D152
BS02 CA A D2173 E2175 N2202 D2310 D200 E202 N225 D333
BS03 CA A D2327 T2351 D2353 D2474 D350 T374 D376 D497
BS04 CA A N2522 N2524 S2549 L2551 D2657 N545 N547 S572 L574 D680
BS05 ZN A E2399 H2460 E422 H483
Gene Ontology
Molecular Function
GO:0070325 lipoprotein particle receptor binding
Biological Process
GO:0001764 neuron migration
GO:0007417 central nervous system development

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Molecular Function
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Biological Process
External links
PDB RCSB:3a7q, PDBe:3a7q, PDBj:3a7q
PDBsum3a7q
PubMed20223215
UniProtQ60841|RELN_MOUSE Reelin (Gene Name=Reln)

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