Structure of PDB 3a7a Chain A

Receptor sequence
>3a7aA (length=337) Species: 83333 (Escherichia coli K-12) [Search protein sequence]
STLRLLISDSYDPWFNLAVEECIFRQMPATQRVLFLWRNADTVVIGRAQN
PWKECNTRRMEEDNVRLARRSSGGGAVFHDLGNTCFTFMAGKPEYDKTIS
TSIVLNALNALGVSAEASGRNDLVVKTVEGDRKVSGSAYRETKDRGFHHG
TLLLNADLSRLANYLNPDKKKLAAKGITSVRSRVTNLTELLPGITHEQVC
EAITEAFFAHYGERVEAEIISPNKTPDLPNFAETFARQSSWEWNFGQAPA
FSHLLDERFTWGGVELHFDVEKGHITRAQVFTDSLNPAPLEALAGRLQGC
LYRADMLQQECEALLVDFPEQEKELRELSAWMAGAVR
3D structure
PDB3a7a Global conformational change associated with the two-step reaction catalyzed by Escherichia coli lipoate-protein ligase A.
ChainA
Resolution3.1 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 6.3.1.20: lipoate--protein ligase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 AMP A G75 V77 F78 K133 T151 L153 V180 R181 S182 V184 G75 V77 F78 K133 T151 L153 V180 R181 S182 V184
Gene Ontology
Molecular Function
GO:0005524 ATP binding
GO:0016874 ligase activity
GO:0016979 lipoate-protein ligase activity
GO:0017118 lipoyltransferase activity
Biological Process
GO:0009249 protein lipoylation
GO:0036211 protein modification process
Cellular Component
GO:0005737 cytoplasm
GO:0005829 cytosol

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:3a7a, PDBe:3a7a, PDBj:3a7a
PDBsum3a7a
PubMed20089862
UniProtP32099|LPLA_ECOLI Lipoate-protein ligase A (Gene Name=lplA)

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