Structure of PDB 3a1c Chain A

Receptor sequence
>3a1cA (length=267) Species: 2234 (Archaeoglobus fulgidus) [Search protein sequence]
AELGILIKNADALEVAEKVTAVIFDKTGTLTKGKPEVTDLVPLNGDEREL
LRLAAIAERRSEHPIAEAIVKKALEHGIELGEPEKVEVIAGEGVVADGIL
VGNKRLMEDFGVAVSNEVELALEKLEREAKTAVIVARNGRVEGIIAVSDT
LKESAKPAVQELKRMGIKVGMITGDNWRSAEAISRELNLDLVIAEVLPHQ
KSEEVKKLQAKEVVAFVGDGINDAPALAQADLGIAVGSGSDVAVESGDIV
LIRDDLRDVVAAIQLSR
3D structure
PDB3a1c Nucleotide recognition by CopA, a Cu+-transporting P-type ATPase.
ChainA
Resolution1.85 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) D424 D618 D622
Catalytic site (residue number reindexed from 1) D25 D219 D223
Enzyme Commision number 7.2.2.8: P-type Cu(+) transporter.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ACP A D424 T426 E457 H462 I464 G490 E491 G492 N502 V532 T572 G573 D574 K600 D25 T27 E58 H63 I65 G91 E92 G93 N103 V133 T173 G174 D175 K201 MOAD: Kd~0.1mM
PDBbind-CN: -logKd/Ki=4.00,Kd=0.1mM
Gene Ontology
Molecular Function
GO:0000166 nucleotide binding
GO:0005215 transporter activity
GO:0005524 ATP binding
GO:0016887 ATP hydrolysis activity
Cellular Component
GO:0016020 membrane

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Molecular Function
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Cellular Component
External links
PDB RCSB:3a1c, PDBe:3a1c, PDBj:3a1c
PDBsum3a1c
PubMed19478797
UniProtO29777|COPA_ARCFU Probable copper-exporting P-type ATPase (Gene Name=copA)

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